Klinik für Frauenheilkunde und Geburtshilfe - Lehrstuhl der Universität Regensburg

Publikationen

(ab 2004)

Schüler-Toprak S, Treeck O, Ortmann O.
Human Chorionic Gonadotropin and Breast Cancer.
Int J Mol Sci. 2017 Jul 21;18(7).

Schüler-Toprak S, Moehle C, Skrzypczak M, Ortmann O, Treeck O.
Effect of estrogen receptor
β agonists on proliferation and gene expression of ovarian cancer cells.
BMC Cancer. 2017 May 8;17(1):319.

Herz C, Tran HTT, Landerer S, Gaus J, Schlotz N, Lehr L, Schäfer WR, Treeck O, Odongo GA, Skatchkov I, Lamy E. Normal human immune cells are sensitive to telomerase inhibition by Brassica-derived 3,3-diindolylmethane,partly mediated via ERα/β-AP1 signaling.
Mol Nutr Food Res. 2017 Sep;61(9).

Schüler-Toprak S, Häring J, Inwald EC, Moehle C, Ortmann O, Treeck O.
Agonists and knockdown of estrogen receptor
β differentially affect invasion of triple-negative breast cancer cells in vitro.
BMC Cancer. 2016 Dec 21;16(1):951.

Skrzypczak M, Merx I, Schüler-Toprak S, Weber F, Inwald EC, Ortmann O, Treeck O.
Molecular profiling of estrogen receptor
α and progesterone receptor transcript variants in endometrial cancer. Steroids. 2015 Dec;104:122-8.

Inwald EC, Koller M, Klinkhammer-Schalke M, Zeman F, Hofstädter F, Lindberg P, Gerstenhauer M, Schüler S, Treeck O, Ortmann O.
Adjuvant endocrine therapy in pre- versus postmenopausal patients with steroid hormone receptor-positive breast cancer: results from a large population-based cohort of a cancer registry.
J Cancer Res Clin Oncol. 2015 Dec;141(12):2229-40

Kwok CW, Treeck O, Buchholz S, Seitz S, Ortmann O, Engel JB. Receptors for
luteinizing hormone-releasing hormone (GnRH) as therapeutic targets in triple negative breast cancers (TNBC). Target Oncol. 2015 Sep;10(3):365-73.

Schüler S, Lattrich C, Skrzypczak M, Fehm T, Ortmann O, Treeck O.
Polymorphisms in the promoter region of ESR2 gene and susceptibility to ovarian cancer.

Gene. 2014 Aug 10;546(2):283-7.

Schüler S, Lattrich C, Skrzypczak M, Fehm T, Ortmann O, Treeck O.
Icb-1 gene polymorphism rs1467465 is associated with susceptibility to ovarian cancer.
J Ovarian Res. 2014 Apr 23;7:42.

Diller M, Schüler S, Buchholz S, Lattrich C, Treeck O, Ortmann O.
Effects of estriol on growth, gene expression and estrogen response element activation in human breast cancer cell lines.
Maturitas. 2014 Apr;77(4):336-43.

Skrzypczak M, Lattrich C, Häring J, Schüler S, Ortmann O, Treeck O.
Expression of SCUBE2 gene declines in high grade endometrial cancer and associates with expression of steroid hormone receptors and tumor suppressor PTEN.
Gynecol Endocrinol. 2013 Dec;29(12):1031-5.

Lattrich C, Häring J, Schüler S, Skrzypczak M, Ortmann O, Treeck O.
Polymorphisms in the promoter region of estrogen receptor
β gene in endometrial cancer.
Arch Gynecol Obstet. 2014 Mar;289(3):631-5.

Skrzypczak M, Schüler S, Lattrich C, Ignatov A, Ortmann O, Treeck O.
G protein-coupled estrogen receptor (GPER) expression in endometrial adenocarcinoma and effect of agonist G-1 on growth of endometrial adenocarcinoma cell lines.
Steroids. 2013 Nov;78(11):1087-91.

Lattrich C, Schüler S, Häring J, Skrzypczak M, Ortmann O, Treeck O.
Effects of a combined treatment with tamoxifen and estrogen receptor
β agonists on human breast cancer cell lines.
Arch Gynecol Obstet. 2014 Jan;289(1):163-71.

Ignatov T, Modl S, Thulig M, Weißenborn C, Treeck O, Ortmann O, Zenclussen A, Costa SD, Kalinski T, Ignatov A. GPER-1 acts as a tumor suppressor in ovarian cancer.
J Ovarian Res. 2013 Jul 13;6(1):51.

Skrzypczak M, Kapka-Skrzypczak L, Cyranka M, Treeck O, Wrobel A, Matosiuk D.
Nuclear estrogen receptors co-activation mechanisms.
Curr Med Chem. 2013;20(27):3317-38.

Treeck O, Schüler S, Häring J, Skrzypczak M, Lattrich C, Ortmann O.
icb-1 Gene counteracts growth of ovarian cancer cell lines.
Cancer Lett. 2013 Jul 28;335(2):441-6.

Lattrich C, Stegerer A, Häring J, Schüler S, Ortmann O, Treeck O.
Estrogen receptor
β agonists affect growth and gene expression of human breast cancer cell lines.
Steroids. 2013 Feb;78(2):195-202.

Häring J, Schüler S, Lattrich C, Ortmann O, Treeck O.
Role of estrogen receptor
β in gynecological cancer.
Gynecol Oncol. 2012 Dec;127(3):673-6.

Süllner J, Lattrich C, Häring J, Görse R, Ortmann O, Treeck O.
A polymorphism in the nuclear receptor coactivator 7 gene and breast cancer susceptibility.
Oncol Lett. 2012 Jan;3(1):131-134.

Lattrich C, Müller AK, Schüler S, Häring J, Ruoff A, Treeck O, Ortmann O.
Single nucleotide polymorphisms in the regulatory region of gonadotropin-releasing hormone receptor gene and breast cancer susceptibility.
Oncol Rep. 2012 Sep;28(3):1091-5.

Treeck O, Belgutay D, Häring J, Schüler S, Lattrich C, Ortmann O.
Network analysis of icb-1 gene function in human breast cancer cells.
J Cell Biochem. 2012 Sep;113(9):2979-88.

Lubig J, Lattrich C, Springwald A, Häring J, Schüler S, Ortmann O, Treeck O.
Effects of a combined treatment with GPR30 agonist G-1 and herceptin on growth and gene expression of human breast cancer cell lines.

Cancer Invest. 2012Jun;30(5):372-9.

Skrzypczak M, Springwald A, Lattrich C, Häring J, Schüler S, Ortmann O, Treeck O.
Expression of cysteine protease cathepsin L is increased in endometrial cancer and correlates with expression of growth regulatory genes.
Cancer Invest. 2012 Jun;30(5):398-403

Häring J, Skrzypczak M, Stegerer A, Lattrich C, Weber F, Görse R, Ortmann O, Treeck O.
Estrogen receptor
β transcript variants associate with oncogene expression in endometrial cancer.
Int J Mol Med. 2012 Jun;29(6):1127-36.

Haselberger M, Springwald A, Konwisorz A, Lattrich C, Goerse R, Ortmann O, Treeck O.
Silencing of the icb-1 gene inhibits the induction of differentiation-associated genes by vitamin D3 and all-trans retinoic acid in gynecological cancer cells.
Int J Mol Med. 2011 Jul;28(1):121-7.

Lattrich C, Lubig J, Springwald A, Goerse R, Ortmann O, Treeck O.
Additive effects of trastuzumab and genistein on human breast cancer cells.
Anticancer Drugs. 2011 Mar;22(3):253-61.

Juhasz-Böss I, Fischer C, Lattrich C, Skrzypczak M, Malik E, Ortmann O, Treeck O.
Endometrial expression of estrogen receptor
β and its splice variants in patients with and without endometriosis.
Arch Gynecol Obstet. 2011 Oct;284(4):885-91.

Springwald A, Lattrich C, Skrzypczak M, Goerse R, Ortmann O, Treeck O.
Identification of novel transcript variants of estrogen receptor
α, β and progesterone receptor gene in human endometrium.
Endocrine. 2010 Jun;37(3):415-24.

Springwald A, Lattrich C, Skrzypczak M, Goerse R, Ortmann O, Treeck O.
Icb-1 Gene expression is elevated in human endometrial adenocarcinoma and is closely associated with HER2 expression.
Cancer Invest. 2010 Nov;28(9):904-9.

Konwisorz A, Springwald A, Haselberger M, Goerse R, Ortmann O, Treeck O.
Knockdown of ICB-1 gene enhanced estrogen responsiveness of ovarian and breast cancer cells.
Endocr Relat Cancer. 2010 Feb 18;17(1):147-57.

Schimanski S, Wild PJ, Treeck O, Horn F, Sigruener A, Rudolph C, Blaszyk H, Klinkhammer-Schalke M, Ortmann O, Hartmann A, Schmitz G.
Expression of the lipid transporters ABCA3 and ABCA1 is diminished in human breast cancer tissue.
Horm Metab Res. 2010 Feb;42(2):102-9.

Giess M, Lattrich C, Springwald A, Goerse R, Ortmann O, Treeck O.
GPR30 gene polymorphisms are associated with progesterone receptor status and histopathological characteristics of breast cancer patients.
J Steroid Biochem Mol Biol. 2010 Jan;118(1-2):7-12.

Fischer C, Juhasz-Boess I, Lattrich C, Ortmann O, Treeck O.
Estrogen receptor beta gene polymorphisms and susceptibility to uterine fibroids.
Gynecol Endocrinol. 2010 Jan;26(1):4-9.

Pfeiler G, Treeck O, Wenzel G, Goerse R, Hartmann A, Schmitz G, Ortmann O.
Influence of insulin resistance on adiponectin receptor expression in breast cancer.
Maturitas. 2009 Jul 20;63(3):253-6.

Treeck O, Lattrich C, Springwald A, Ortmann O.
Estrogen receptor beta exerts growth-inhibitory effects on human mammary epithelial cells.
Breast Cancer Res Treat. 2010 Apr;120(3):557-65.

Treeck O, Elemenler E, Kriener C, Horn F, Springwald A, Hartmann A, Ortmann O.
Polymorphisms in the promoter region of ESR2 gene and breast cancer susceptibility.
J Steroid Biochem Mol Biol. 2009 Apr;114(3-5):207-11.

Pfeiler G, Treeck O, Wenzel G, Goerse R, Hartmann A, Schmitz G, Ortmann O.
Correlation of body mass index and menopausal status with the intra-tumoral estrogen system in invasive breast cancer.
Gynecol Endocrinol. 2009 Mar;25(3):183-7.

Springwald A, Lattrich C, Seitz S, Ortmann O, Treeck O.
Single nucleotide polymorphisms in human gene icb-1 and breast cancer susceptibility.
Cancer Invest. 2009 Jul;27(6):669-72.

Treeck O, Lattrich C, Juhasz-Boess I, Buchholz S, Pfeiler G, Ortmann O.
Adiponectin differentially affects gene expression in human mammary epithelial and breast cancer cells.
Br J Cancer. 2008 Oct 21;99(8):1246-50.

Lattrich C, Juhasz-Boess I, Ortmann O, Treeck O.
Detection of an elevated HER2 expression in MCF-7 breast cancer cells overexpressing estrogen receptor beta1.

Oncol Rep. 2008 Mar;19(3):811-7.

Pfeiler GH, Buechler C, Neumeier M, Schäffler A, Schmitz G, Ortmann O, Treeck O.
Adiponectin effects on human breast cancer cells are dependent on 17-beta estradiol.
Oncol Rep. 2008 Mar;19(3):787-93.

Bollmann J, Ortmann O, Treeck O.
Expression of differentiation-associated gene icb-1 is estrogen-responsive in ovarian and breast cancer cell lines.
J Steroid Biochem Mol Biol. 2008 Mar;109(1-2):16-21.

Pfeiler G, Horn F, Lattrich C, Klappenberger S, Ortmann O, Treeck O.
Apoptotic effects of signal transduction inhibitors on human tumor cells with different PTEN expression.
Oncol Rep. 2007 Nov;18(5):1305-9.

Treeck O, Juhasz-Boess I, Lattrich C, Horn F, Goerse R, Ortmann O.
Effects of exon-deleted estrogen receptor beta transcript variants on growth, apoptosis and gene expression of human breast cancer cell lines.
Breast Cancer Res Treat. 2008 Aug;110(3):507-20.

Treeck O, Pfeiler G, Mitter D, Lattrich C, Piendl G, Ortmann O.
Estrogen receptor {beta}1 exerts antitumoral effects on SK-OV-3 ovarian cancer cells.
J Endocrinol. 2007 Jun;193(3):421-33.

Sanders L,Görse R, Treeck O , Ortmann O
Benigne Brusterkrankungen - Ätiologie und Klinik.
Geburtshilfe und Frauenheilkunde 2007; 67, 321-328.

Weiss JM, Hüller H, Polack S, Friedrich M, Diedrich K, Treeck O, Pfeiler G, Ortmann O.
Estradiol differentially modulates the exocytotic proteins SNAP-25 and munc-18 in pituitary gonadotrophs.
J Mol Endocrinol. 2007 Feb;38(1-2):305-14.

Weiss JM, Polack S, Treeck O, Diedrich K, Ortmann O.
Regulation of GnRH I receptor gene expression by the GnRH agonist triptorelin, estradiol, and progesterone in the gonadotroph-derived cell line alphaT3-1.
Endocrine. 2006 Aug;30(1):139-44.

Treeck O, Pfeiler G, Horn F, Federhofer B, Houlihan H, Vollmer A, Ortmann O.
Novel estrogen receptor beta transcript variants identified in human breast cancer cells affect cell growth and apoptosis of COS-1 cells.
Mol Cell Endocrinol. 2007 Jan 29;264(1-2):50-60.

Treeck O, Wackwitz B, Haus U, Ortmann O.
Effects of a combined treatment with mTOR inhibitor RAD001 and tamoxifen in vitro on growth and apoptosis of human cancer cells.
Gynecol Oncol. 2006 Aug;102(2):292-9.

Pfeiler GH, Lattrich C, Schambeck C, Langmann T, Treeck O , Ortmann O
Metabolismus und Mammakarzinom.
Geburtshilfe und Frauenheilkunde 2006; 66, 841-851.

Juhasz-Böss I, Treeck O , Malik E, Ortmann O
Aromatasehemmer in der Therapie der Endometriose.
Gynäkologische Endokrinologie 2006;4, 174-180.

Treeck O, Haldar C, Ortmann O.
Antiestrogens modulate MT1 melatonin receptor expression in breast and ovarian cancer cell lines.
Oncol Rep. 2006 Jan;15(1):231-5.

Treeck O, Kindzorra I, Pauser K, Treeck L, Ortmann O.
Expression of icb-1 gene is interferon-gamma inducible in breast and ovarian cancer cell lines and affects the IFN gamma-response of SK-OV-3 ovarian cancer cells.
Cytokine. 2005 Nov 3;32(3-4):137-42.

Mitter D, Ortmann O, Treeck O
Östrogenrezeptor-β-Isoformen - Funktionen und klinische Bedeutung bei Brustkrebs.
Zentralblatt für Gynäkologie 2005; 127, 28-34.

Zhou R, Treeck O, Horn F, Ortmann O.
Effects of prolonged tamoxifen treatment on receptor expression and apoptosis of ovarian cancer cells.
Gynecol Oncol.
2005Mar;96(3):678-83.

Treeck O, Zhou R, Diedrich K, Ortmann O.
Tamoxifen long-term treatment in vitro alters the apoptotic response of MCF-7 breast cancer cells.
Anticancer Drugs. 2004 Sep;15(8):787-93.

Babilas K, Treeck O, Ortmann O
Hormonersatztherapie und gynäkologische Malignome.
Medizinische Welt 2004; 1-2, 1-4.

Treeck O, Horn F, Ortmann O
Endokrine Resistenzmechanismen - Schwerpunkt Mammakarzinom.
GynSpectrum 2004; 3, 13-16.

Treeck O, Diedrich K, Ortmann O
Interaktionen zwischen Östrogenrezeptor- und Rezeptor-Tyrosinkinase- Signaltransduktion.
Tumordiagnose und Therapie 2004; 25, 35-42.

Chen D, Hackl W, Ortmann O, Treeck O.
Effects of a combination of exemestane and paclitaxel on human tumor cells in vitro.
Anticancer Drugs. 2004 Jan;15(1):55-61.

Buchkapitel

Treeck O
Einführung in die Endokrinologie.
In: Klinische Endokrinologie für Frauenärzte 2008. Hrsg.: FA Leidenberger, T Strowitzki, O Ortmann. Heidelberg: Springer Medizin Verlag

Treeck O und Ortmann O
Endokrinium und Tumorwachstum.
In: Klinische Endokrinologie für Frauenärzte 2008. Hrsg.: FA Leidenberger, T Strowitzki, O Ortmann. Heidelberg: Springer Medizin Verlag

 

Kontaktieren Sie uns

Prof. Dr. rer. nat.
Oliver Treeck
Forschungsleiter Molekulare Onkologie      
 
Telefon 0941 782-7520
Mail otreeck@caritasstjosef.de

 

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